BRD-K41185612_NCGC00187483-01_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

21 genes differentially expressed following the BRD-K41185612_NCGC00187483-01_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
IGFBP3 insulin-like growth factor binding protein 3
LAMP5 lysosomal-associated membrane protein family, member 5
LDOC1 leucine zipper, down-regulated in cancer 1

decreased expression

Symbol Name
BIRC3 baculoviral IAP repeat containing 3
CCL19 chemokine (C-C motif) ligand 19
CP ceruloplasmin (ferroxidase)
CXCL9 chemokine (C-X-C motif) ligand 9
F3 coagulation factor III (thromboplastin, tissue factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGF1R insulin-like growth factor 1 receptor
MMP10 matrix metallopeptidase 10
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
PTGDS prostaglandin D2 synthase 21kDa (brain)
SERINC5 serine incorporator 5
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SGK1 serum/glucocorticoid regulated kinase 1
SNAI2 snail family zinc finger 2
TOP2A topoisomerase (DNA) II alpha 170kDa
USP22 ubiquitin specific peptidase 22
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon