BRD-K40656405_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K40656405_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANXA1 annexin A1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFI complement factor I
CXCL8 chemokine (C-X-C motif) ligand 8
ELOVL6 ELOVL fatty acid elongase 6
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL2 four and a half LIM domains 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL1 FOS-like antigen 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLUL glutamate-ammonia ligase
IGFBP7 insulin-like growth factor binding protein 7
LTF lactotransferrin
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MGLL monoglyceride lipase
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPO myeloperoxidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NREP neuronal regeneration related protein
PLIN2 perilipin 2
PLK2 polo-like kinase 2
RPS11 ribosomal protein S11
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCG5 secretogranin V
SEPP1 selenoprotein P, plasma, 1
TACSTD2 tumor-associated calcium signal transducer 2
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR4 toll-like receptor 4

decreased expression

Symbol Name
ARID5B AT rich interactive domain 5B (MRF1-like)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CCNG2 cyclin G2
CREBL2 cAMP responsive element binding protein-like 2
FGFR2 fibroblast growth factor receptor 2
HIST1H4C histone cluster 1, H4c
HOXA10 homeobox A10
MACF1 microtubule-actin crosslinking factor 1
TMSB15A thymosin beta 15a