BRD-K40255344_EI-215_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K40255344_EI-215_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AREG amphiregulin
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BHLHE40 basic helix-loop-helix family, member e40
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DHCR7 7-dehydrocholesterol reductase
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
F11R F11 receptor
FAR2 fatty acyl CoA reductase 2
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
GADD45B growth arrest and DNA-damage-inducible, beta
GTPBP2 GTP binding protein 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IER3 immediate early response 3
INSIG1 insulin induced gene 1
JUNB jun B proto-oncogene
KDM7A lysine (K)-specific demethylase 7A
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
LPIN1 lipin 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MMP3 matrix metallopeptidase 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NBPF10 neuroblastoma breakpoint family, member 10
NEBL nebulette
NPC1 Niemann-Pick disease, type C1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSAT1 phosphoserine aminotransferase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100P S100 calcium binding protein P
SAT1 spermidine/spermine N1-acetyltransferase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SIK1 salt-inducible kinase 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOX4 SRY (sex determining region Y)-box 4
TGIF1 TGFB-induced factor homeobox 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TSC22D1 TSC22 domain family, member 1
TSC22D3 TSC22 domain family, member 3
VCAN versican

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
AIM1 absent in melanoma 1
B3GNT1
CDC25A cell division cycle 25A
COL3A1 collagen, type III, alpha 1
CXCL13 chemokine (C-X-C motif) ligand 13
DEGS1 delta(4)-desaturase, sphingolipid 1
GJA1 gap junction protein, alpha 1, 43kDa
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MSMB microseminoprotein, beta-
NR2F1 nuclear receptor subfamily 2, group F, member 1
PCNA proliferating cell nuclear antigen
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
REEP1 receptor accessory protein 1
TMEM14A transmembrane protein 14A
TSPAN7 tetraspanin 7
WFS1 Wolfram syndrome 1 (wolframin)