BRD-K40175214_torin-1_SKBR3_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-K40175214_torin-1_SKBR3_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACACB acetyl-CoA carboxylase beta
AUTS2 autism susceptibility candidate 2
BCHE butyrylcholinesterase
BECN1 beclin 1, autophagy related
BTG1 B-cell translocation gene 1, anti-proliferative
CCL5 chemokine (C-C motif) ligand 5
CD9 CD9 molecule
CDK14 cyclin-dependent kinase 14
DUSP4 dual specificity phosphatase 4
FAM171A1 family with sequence similarity 171, member A1
GATA3 GATA binding protein 3
IFITM1 interferon induced transmembrane protein 1
IQGAP1 IQ motif containing GTPase activating protein 1
KLHL24 kelch-like family member 24
LGALS1 lectin, galactoside-binding, soluble, 1
LGMN legumain
MAST4 microtubule associated serine/threonine kinase family member 4
MECOM MDS1 and EVI1 complex locus
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLAU plasminogen activator, urokinase
PTX3 pentraxin 3, long
RND3 Rho family GTPase 3
SFRP1 secreted frizzled-related protein 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRPX sushi-repeat containing protein, X-linked
TFF1 trefoil factor 1
TUBA1A tubulin, alpha 1a

decreased expression

Symbol Name
AQP1 aquaporin 1 (Colton blood group)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CCNE2 cyclin E2
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DHCR24 24-dehydrocholesterol reductase
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EREG epiregulin
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
HBB hemoglobin, beta
HIST1H1C histone cluster 1, H1c
IGFBP4 insulin-like growth factor binding protein 4
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
LYZ lysozyme
MSMB microseminoprotein, beta-
NEFH neurofilament, heavy polypeptide
NEFM neurofilament, medium polypeptide
NKX3-1 NK3 homeobox 1
NPR3 natriuretic peptide receptor 3
RPIA ribose 5-phosphate isomerase A
S100A9 S100 calcium binding protein A9
S100P S100 calcium binding protein P
SCAND1 SCAN domain containing 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SNAP25 synaptosomal-associated protein, 25kDa
STMN2 stathmin 2
TFRC transferrin receptor