BRD-K40175214_torin-1_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

63 genes differentially expressed following the BRD-K40175214_torin-1_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ALCAM activated leukocyte cell adhesion molecule
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BHLHE40 basic helix-loop-helix family, member e40
BMP6 bone morphogenetic protein 6
BTG1 B-cell translocation gene 1, anti-proliferative
C2CD5 C2 calcium-dependent domain containing 5
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
FOXO3 forkhead box O3
FXYD3 FXYD domain containing ion transport regulator 3
GADD45B growth arrest and DNA-damage-inducible, beta
IPO13 importin 13
IRS2 insulin receptor substrate 2
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
JMJD1C jumonji domain containing 1C
LDLR low density lipoprotein receptor
LEF1 lymphoid enhancer-binding factor 1
LMCD1 LIM and cysteine-rich domains 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MEF2C myocyte enhancer factor 2C
MGP matrix Gla protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NLGN4X neuroligin 4, X-linked
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDGFC platelet derived growth factor C
PECAM1 platelet/endothelial cell adhesion molecule 1
PLAU plasminogen activator, urokinase
PLCB4 phospholipase C, beta 4
PSAP prosaposin
QKI QKI, KH domain containing, RNA binding
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFRP1 secreted frizzled-related protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1

decreased expression

Symbol Name
ANO3 anoctamin 3
BST2 bone marrow stromal cell antigen 2
CALD1 caldesmon 1
CDC25A cell division cycle 25A
CXCL14 chemokine (C-X-C motif) ligand 14
DICER1 dicer 1, ribonuclease type III
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EED embryonic ectoderm development
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
GBP1 guanylate binding protein 1, interferon-inducible
HSPH1 heat shock 105kDa/110kDa protein 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGHM immunoglobulin heavy constant mu
JUN jun proto-oncogene
LRRC17 leucine rich repeat containing 17
NRIP1 nuclear receptor interacting protein 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RHOBTB3 Rho-related BTB domain containing 3
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SESN1 sestrin 1
TRAF5 TNF receptor-associated factor 5
ZC3HAV1 zinc finger CCCH-type, antiviral 1