BRD-K40175214_torin-1_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K40175214_torin-1_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOD apolipoprotein D
BCL2 B-cell CLL/lymphoma 2
CLEC2B C-type lectin domain family 2, member B
CLU clusterin
CP ceruloplasmin (ferroxidase)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL9 chemokine (C-X-C motif) ligand 9
FCGBP Fc fragment of IgG binding protein
FN1 fibronectin 1
GLUL glutamate-ammonia ligase
GPX3 glutathione peroxidase 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
MARCKSL1 MARCKS-like 1
MTUS1 microtubule associated tumor suppressor 1
PCP4 Purkinje cell protein 4
PRUNE2 prune homolog 2 (Drosophila)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RBL2 retinoblastoma-like 2
RBPMS RNA binding protein with multiple splicing
SAT1 spermidine/spermine N1-acetyltransferase 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TXNIP thioredoxin interacting protein
WT1 Wilms tumor 1
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CD58 CD58 molecule
CPM carboxypeptidase M
CXCL2 chemokine (C-X-C motif) ligand 2
ELF5 E74-like factor 5 (ets domain transcription factor)
ENO1 enolase 1, (alpha)
F13A1 coagulation factor XIII, A1 polypeptide
FADS1 fatty acid desaturase 1
FAS Fas cell surface death receptor
FXYD3 FXYD domain containing ion transport regulator 3
HN1 hematological and neurological expressed 1
HOXC10 homeobox C10
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
MME membrane metallo-endopeptidase
NR2F2 nuclear receptor subfamily 2, group F, member 2
PCNA proliferating cell nuclear antigen
SFN stratifin
TFRC transferrin receptor