BRD-K40175214_torin-1_LNCAP_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-K40175214_torin-1_LNCAP_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ANO1 anoctamin 1, calcium activated chloride channel
ARID5B AT rich interactive domain 5B (MRF1-like)
BCL2A1 BCL2-related protein A1
CGA glycoprotein hormones, alpha polypeptide
CLEC2B C-type lectin domain family 2, member B
CX3CR1 chemokine (C-X3-C motif) receptor 1
DEPTOR DEP domain containing MTOR-interacting protein
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GADD45A growth arrest and DNA-damage-inducible, alpha
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10
HAL histidine ammonia-lyase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFI16 interferon, gamma-inducible protein 16
IL6ST interleukin 6 signal transducer
KDM3A lysine (K)-specific demethylase 3A
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT7 keratin 7, type II
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP7 microtubule-associated protein 7
MYBPC1 myosin binding protein C, slow type
MYH11 myosin, heavy chain 11, smooth muscle
MYLK myosin light chain kinase
NAV2 neuron navigator 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
RBM47 RNA binding motif protein 47
SESN1 sestrin 1
SFRP1 secreted frizzled-related protein 1
SFRP4 secreted frizzled-related protein 4
SFTPB surfactant protein B
SOX4 SRY (sex determining region Y)-box 4
SYNM synemin, intermediate filament protein
TKTL1 transketolase-like 1
TLR1 toll-like receptor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM28 tripartite motif containing 28
TSPAN5 tetraspanin 5
VLDLR very low density lipoprotein receptor
VNN1 vanin 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALOX5 arachidonate 5-lipoxygenase
ANXA2 annexin A2
CAPN1 calpain 1, (mu/I) large subunit
CDC25A cell division cycle 25A
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DLC1 DLC1 Rho GTPase activating protein
ECM1 extracellular matrix protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBLN1 fibulin 1
G0S2 G0/G1 switch 2
GCH1 GTP cyclohydrolase 1
HILPDA hypoxia inducible lipid droplet-associated
IFI27 interferon, alpha-inducible protein 27
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
LCN2 lipocalin 2
MAT2A methionine adenosyltransferase II, alpha
NID2 nidogen 2 (osteonidogen)
NR2F2 nuclear receptor subfamily 2, group F, member 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRDX2 peroxiredoxin 2
PSCA prostate stem cell antigen
RHOBTB3 Rho-related BTB domain containing 3
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SNAP25 synaptosomal-associated protein, 25kDa
STMN2 stathmin 2
TUBB2A tubulin, beta 2A class IIa
TUBB6 tubulin, beta 6 class V
WFDC2 WAP four-disulfide core domain 2