BRD-K40175214_torin-1_LNCAP_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K40175214_torin-1_LNCAP_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADA adenosine deaminase
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADCK3 aarF domain containing kinase 3
ARID5B AT rich interactive domain 5B (MRF1-like)
BHLHE40 basic helix-loop-helix family, member e40
CA1 carbonic anhydrase I
CCNG1 cyclin G1
CCNG2 cyclin G2
CD36 CD36 molecule (thrombospondin receptor)
CDK14 cyclin-dependent kinase 14
CLDN3 claudin 3
CLU clusterin
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DSP desmoplakin
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
GOLM1 golgi membrane protein 1
HBP1 HMG-box transcription factor 1
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HOXB2 homeobox B2
IGFBP3 insulin-like growth factor binding protein 3
LTF lactotransferrin
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAGED1 melanoma antigen family D1
MFAP5 microfibrillar associated protein 5
MXI1 MAX interactor 1, dimerization protein
NOTCH3 notch 3
PLAGL1 pleiomorphic adenoma gene-like 1
PLS1 plastin 1
PPAP2B phosphatidic acid phosphatase type 2B
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RPL31 ribosomal protein L31
SEPP1 selenoprotein P, plasma, 1
SETBP1 SET binding protein 1
SOX4 SRY (sex determining region Y)-box 4
SPON1 spondin 1, extracellular matrix protein
STK26 serine/threonine protein kinase 26
TLE2 transducin-like enhancer of split 2
TMPRSS3 transmembrane protease, serine 3
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALCAM activated leukocyte cell adhesion molecule
AQP3 aquaporin 3 (Gill blood group)
C20ORF24 chromosome 20 open reading frame 24
CADM1 cell adhesion molecule 1
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CDC25A cell division cycle 25A
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CSRP1 cysteine and glycine-rich protein 1
CXADR coxsackie virus and adenovirus receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DKK1 dickkopf WNT signaling pathway inhibitor 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GSTM3 glutathione S-transferase mu 3 (brain)
ISG15 ISG15 ubiquitin-like modifier
MAT2A methionine adenosyltransferase II, alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PSAT1 phosphoserine aminotransferase 1
PXDN peroxidasin
RGS4 regulator of G-protein signaling 4
S100A10 S100 calcium binding protein A10
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC1 syndecan 1
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SNAP25 synaptosomal-associated protein, 25kDa
SPINT2 serine peptidase inhibitor, Kunitz type, 2
STC2 stanniocalcin 2
THBS1 thrombospondin 1
TMSB15A thymosin beta 15a
TSPYL5 TSPY-like 5