BRD-K40175214_torin-1_BT20_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K40175214_torin-1_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARID5B AT rich interactive domain 5B (MRF1-like)
C10ORF10 chromosome 10 open reading frame 10
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCNG2 cyclin G2
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DUSP6 dual specificity phosphatase 6
ERBB3 erb-b2 receptor tyrosine kinase 3
GABARAPL1 GABA(A) receptor-associated protein like 1
GADD45B growth arrest and DNA-damage-inducible, beta
GPX3 glutathione peroxidase 3
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INSR insulin receptor
IRS2 insulin receptor substrate 2
KLF9 Kruppel-like factor 9
KLHDC3 kelch domain containing 3
KRT18 keratin 18, type I
MBNL2 muscleblind-like splicing regulator 2
MXI1 MAX interactor 1, dimerization protein
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PROM1 prominin 1
PSD3 pleckstrin and Sec7 domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFRP1 secreted frizzled-related protein 1
SMYD2 SET and MYND domain containing 2
SOX4 SRY (sex determining region Y)-box 4
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
VCAN versican
VEGFA vascular endothelial growth factor A
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BASP1 brain abundant, membrane attached signal protein 1
CCND2 cyclin D2
CDC25A cell division cycle 25A
DACH1 dachshund family transcription factor 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HBEGF heparin-binding EGF-like growth factor
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
JCHAIN joining chain of multimeric IgA and IgM
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
MUC5B mucin 5B, oligomeric mucus/gel-forming
PTGDS prostaglandin D2 synthase 21kDa (brain)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFN stratifin