BRD-K40175214_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

93 genes differentially expressed following the BRD-K40175214_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AEBP1 AE binding protein 1
C6ORF48 chromosome 6 open reading frame 48
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
COL15A1 collagen, type XV, alpha 1
COMP cartilage oligomeric matrix protein
DLK1 delta-like 1 homolog (Drosophila)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HOPX HOP homeobox
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KRT15 keratin 15, type I
LTBP1 latent transforming growth factor beta binding protein 1
LTBP2 latent transforming growth factor beta binding protein 2
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MOXD1 monooxygenase, DBH-like 1
MSLN mesothelin
MYB v-myb avian myeloblastosis viral oncogene homolog
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NUPR1 nuclear protein, transcriptional regulator, 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RNF167 ring finger protein 167
SCEL sciellin
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERINC5 serine incorporator 5
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFRP4 secreted frizzled-related protein 4
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
STAR steroidogenic acute regulatory protein
STX1A syntaxin 1A (brain)
TACSTD2 tumor-associated calcium signal transducer 2
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
THBS1 thrombospondin 1
TSPAN8 tetraspanin 8
TSPYL5 TSPY-like 5
TXNIP thioredoxin interacting protein
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ACOT9 acyl-CoA thioesterase 9
ACTN1 actinin, alpha 1
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
BAD BCL2-associated agonist of cell death
BAG3 BCL2-associated athanogene 3
CA12 carbonic anhydrase XII
CAV1 caveolin 1, caveolae protein, 22kDa
CCNB1 cyclin B1
CCNE2 cyclin E2
CD320 CD320 molecule
CDC20 cell division cycle 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHGB chromogranin B
COL4A6 collagen, type IV, alpha 6
CSRP2 cysteine and glycine-rich protein 2
CYC1 cytochrome c-1
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
EMP3 epithelial membrane protein 3
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FCGBP Fc fragment of IgG binding protein
FHL1 four and a half LIM domains 1
FSCN1 fascin actin-bundling protein 1
FSTL1 follistatin-like 1
GBP1 guanylate binding protein 1, interferon-inducible
HAT1 histone acetyltransferase 1
HBB hemoglobin, beta
HSPA1A heat shock 70kDa protein 1A
JMJD6 jumonji domain containing 6
LAMB1 laminin, beta 1
LGALS1 lectin, galactoside-binding, soluble, 1
PBX1 pre-B-cell leukemia homeobox 1
PFKP phosphofructokinase, platelet
PGAM1 phosphoglycerate mutase 1 (brain)
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
PRNP prion protein
PROM1 prominin 1
PUF60 poly-U binding splicing factor 60KDa
PXMP2 peroxisomal membrane protein 2, 22kDa
REEP1 receptor accessory protein 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SORBS3 sorbin and SH3 domain containing 3
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STIP1 stress-induced phosphoprotein 1
TGFBI transforming growth factor, beta-induced, 68kDa
TRIM14 tripartite motif containing 14
TUBB6 tubulin, beta 6 class V
UBE2S ubiquitin-conjugating enzyme E2S
VDAC1 voltage-dependent anion channel 1