BRD-K39987650_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K39987650_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BRD4 bromodomain containing 4
CENPE centromere protein E, 312kDa
CLU clusterin
CTGF connective tissue growth factor
DUSP1 dual specificity phosphatase 1
EZR ezrin
FGF13 fibroblast growth factor 13
FOS FBJ murine osteosarcoma viral oncogene homolog
KDM3A lysine (K)-specific demethylase 3A
NKTR natural killer cell triggering receptor
NTS neurotensin
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PNISR PNN-interacting serine/arginine-rich protein
PRRC2C proline-rich coiled-coil 2C
PUM1 pumilio RNA-binding family member 1
RBMS1 RNA binding motif, single stranded interacting protein 1
RPL38 ribosomal protein L38
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SFRP1 secreted frizzled-related protein 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SRRM2 serine/arginine repetitive matrix 2
STOM stomatin
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THBS1 thrombospondin 1
ZMYM2 zinc finger, MYM-type 2

decreased expression

Symbol Name
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
BCHE butyrylcholinesterase
BLNK B-cell linker
CCND2 cyclin D2
CCNF cyclin F
CXCL13 chemokine (C-X-C motif) ligand 13
DNM1L dynamin 1-like
F12 coagulation factor XII (Hageman factor)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
H2AFX H2A histone family, member X
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
NRN1 neuritin 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
THYN1 thymocyte nuclear protein 1
TRAPPC4 trafficking protein particle complex 4