BRD-K39965020_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

35 genes differentially expressed following the BRD-K39965020_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ASS1 argininosuccinate synthase 1
CCR1 chemokine (C-C motif) receptor 1
CD163 CD163 molecule
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GCLM glutamate-cysteine ligase, modifier subunit
GLIPR1 GLI pathogenesis-related 1
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IL10RA interleukin 10 receptor, alpha
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
NQO1 NAD(P)H dehydrogenase, quinone 1
PIR pirin (iron-binding nuclear protein)
PTPRO protein tyrosine phosphatase, receptor type, O
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TXNRD1 thioredoxin reductase 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IGFBP3 insulin-like growth factor binding protein 3
LAMB1 laminin, beta 1
SIK1 salt-inducible kinase 1
SKAP2 src kinase associated phosphoprotein 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SRPX sushi-repeat containing protein, X-linked
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN4 tetraspanin 4
VCAN versican
XIST X inactive specific transcript (non-protein coding)