BRD-K39829853_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K39829853_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AMIGO2 adhesion molecule with Ig-like domain 2
BHLHE41 basic helix-loop-helix family, member e41
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CA1 carbonic anhydrase I
CAST calpastatin
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
DDIT4 DNA-damage-inducible transcript 4
ENO2 enolase 2 (gamma, neuronal)
FAM162A family with sequence similarity 162, member A
FLNA filamin A, alpha
GATA2 GATA binding protein 2
GCLC glutamate-cysteine ligase, catalytic subunit
GDF15 growth differentiation factor 15
GPI glucose-6-phosphate isomerase
HBD hemoglobin, delta
HILPDA hypoxia inducible lipid droplet-associated
KANK1 KN motif and ankyrin repeat domains 1
KDM3A lysine (K)-specific demethylase 3A
MET MET proto-oncogene, receptor tyrosine kinase
MMP1 matrix metallopeptidase 1
MMP12 matrix metallopeptidase 12
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
P3H2 prolyl 3-hydroxylase 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGM1 phosphoglucomutase 1
PKM pyruvate kinase, muscle
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PTK2 protein tyrosine kinase 2
PXMP2 peroxisomal membrane protein 2, 22kDa
RALGDS ral guanine nucleotide dissociation stimulator
RPS4Y1 ribosomal protein S4, Y-linked 1
SALL1 spalt-like transcription factor 1
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
SIK1 salt-inducible kinase 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPAG4 sperm associated antigen 4
SRGN serglycin
VEGFA vascular endothelial growth factor A
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
ASPN asporin
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CELF2 CUGBP, Elav-like family member 2
CLEC2B C-type lectin domain family 2, member B
COL3A1 collagen, type III, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FABP4 fatty acid binding protein 4, adipocyte
FGG fibrinogen gamma chain
GPC3 glypican 3
HOXA5 homeobox A5
HOXC6 homeobox C6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
LDB2 LIM domain binding 2
MAGEA3 melanoma antigen family A3
MFAP4 microfibrillar-associated protein 4
MTDH metadherin
NR2F6 nuclear receptor subfamily 2, group F, member 6
NUSAP1 nucleolar and spindle associated protein 1
PEG10 paternally expressed 10
TGFBR3 transforming growth factor, beta receptor III
WT1 Wilms tumor 1