BRD-K39733634_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

74 genes differentially expressed following the BRD-K39733634_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATG3 autophagy related 3
BASP1 brain abundant, membrane attached signal protein 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
DCTD dCMP deaminase
EAPP E2F-associated phosphoprotein
GDF15 growth differentiation factor 15
GRIA2 glutamate receptor, ionotropic, AMPA 2
HOXB7 homeobox B7
HOXC6 homeobox C6
IRS2 insulin receptor substrate 2
MALL mal, T-cell differentiation protein-like
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MET MET proto-oncogene, receptor tyrosine kinase
NOTCH2 notch 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRGN neurogranin (protein kinase C substrate, RC3)
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEX11A peroxisomal biogenesis factor 11 alpha
PF4 platelet factor 4
PON2 paraoxonase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
R3HDM1 R3H domain containing 1
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
TBC1D4 TBC1 domain family, member 4
TFPI2 tissue factor pathway inhibitor 2
TLR4 toll-like receptor 4
TMEM123 transmembrane protein 123
VCAN versican

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADA adenosine deaminase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ATF3 activating transcription factor 3
BMP2 bone morphogenetic protein 2
CD24 CD24 molecule
CD9 CD9 molecule
CHGB chromogranin B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLU clusterin
CNPY3 canopy FGF signaling regulator 3
CPE carboxypeptidase E
CXCL14 chemokine (C-X-C motif) ligand 14
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DPT dermatopontin
EDNRA endothelin receptor type A
ELN elastin
EPHA3 EPH receptor A3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM107A family with sequence similarity 107, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FST follistatin
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLUL glutamate-ammonia ligase
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GPM6B glycoprotein M6B
GPNMB glycoprotein (transmembrane) nmb
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
JUN jun proto-oncogene
MT1E metallothionein 1E
NEBL nebulette
PTN pleiotrophin
RHOH ras homolog family member H
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SPARCL1 SPARC-like 1 (hevin)
SPINK1 serine peptidase inhibitor, Kazal type 1
TAGLN transgelin
TIMP3 TIMP metallopeptidase inhibitor 3
VEGFA vascular endothelial growth factor A
VSIG4 V-set and immunoglobulin domain containing 4