BRD-K39345836_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

72 genes differentially expressed following the BRD-K39345836_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD4 abhydrolase domain containing 4
ADD3 adducin 3 (gamma)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CBR3 carbonyl reductase 3
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLNS1A chloride channel, nucleotide-sensitive, 1A
COMP cartilage oligomeric matrix protein
DEFB1 defensin, beta 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF5A eukaryotic translation initiation factor 5A
FOSL1 FOS-like antigen 1
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PIR pirin (iron-binding nuclear protein)
PPAP2B phosphatidic acid phosphatase type 2B
PTGES prostaglandin E synthase
PTX3 pentraxin 3, long
RAP1GAP RAP1 GTPase activating protein
RPL37A ribosomal protein L37a
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
TALDO1 transaldolase 1
TM4SF1 transmembrane 4 L six family member 1
TSKU tsukushi, small leucine rich proteoglycan
TXN thioredoxin
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AMIGO2 adhesion molecule with Ig-like domain 2
BCHE butyrylcholinesterase
C7 complement component 7
CCL5 chemokine (C-C motif) ligand 5
CD36 CD36 molecule (thrombospondin receptor)
CD8A CD8a molecule
CDH3 cadherin 3, type 1, P-cadherin (placental)
DMXL2 Dmx-like 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
GNAS GNAS complex locus
GNLY granulysin
GPNMB glycoprotein (transmembrane) nmb
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MTA1 metastasis associated 1
NPIPB3 nuclear pore complex interacting protein family, member B3
PDLIM3 PDZ and LIM domain 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PRF1 perforin 1 (pore forming protein)
PRSS8 protease, serine, 8
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PXDN peroxidasin
RFTN1 raftlin, lipid raft linker 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TMEM176B transmembrane protein 176B
TSPAN5 tetraspanin 5
VDAC1 voltage-dependent anion channel 1