BRD-K39232234_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

72 genes differentially expressed following the BRD-K39232234_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARL4A ADP-ribosylation factor-like 4A
CA12 carbonic anhydrase XII
CAV1 caveolin 1, caveolae protein, 22kDa
CD69 CD69 molecule
CES1 carboxylesterase 1
CFD complement factor D (adipsin)
CSRP2 cysteine and glycine-rich protein 2
CST3 cystatin C
CTSB cathepsin B
EMP1 epithelial membrane protein 1
FOSL1 FOS-like antigen 1
FOXJ3 forkhead box J3
G6PD glucose-6-phosphate dehydrogenase
GPX3 glutathione peroxidase 3
HACD1 3-hydroxyacyl-CoA dehydratase 1
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HILPDA hypoxia inducible lipid droplet-associated
HMOX1 heme oxygenase 1
HSPB8 heat shock 22kDa protein 8
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IL1R2 interleukin 1 receptor, type II
IQGAP2 IQ motif containing GTPase activating protein 2
IRS2 insulin receptor substrate 2
LAMP1 lysosomal-associated membrane protein 1
MALL mal, T-cell differentiation protein-like
MYH11 myosin, heavy chain 11, smooth muscle
MYOF myoferlin
NR0B1 nuclear receptor subfamily 0, group B, member 1
PI3 peptidase inhibitor 3, skin-derived
PIR pirin (iron-binding nuclear protein)
PLAC8 placenta-specific 8
PPAP2B phosphatidic acid phosphatase type 2B
PTGES prostaglandin E synthase
RRAGD Ras-related GTP binding D
S100P S100 calcium binding protein P
SLC38A1 solute carrier family 38, member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPARCL1 SPARC-like 1 (hevin)
SPRR2B small proline-rich protein 2B
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TKT transketolase
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ARMCX1 armadillo repeat containing, X-linked 1
CLDN10 claudin 10
CPE carboxypeptidase E
HNMT histamine N-methyltransferase
IDO1 indoleamine 2,3-dioxygenase 1
IGHM immunoglobulin heavy constant mu
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRDX2 peroxiredoxin 2
PSRC1 proline/serine-rich coiled-coil 1
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SST somatostatin
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TUBB4B tubulin, beta 4B class IVb
VCAN versican
ZIC1 Zic family member 1
ZNF586 zinc finger protein 586