BRD-K39187410_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K39187410_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C3 aldo-keto reductase family 1, member C3
CCNA1 cyclin A1
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL1 four and a half LIM domains 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IGKC immunoglobulin kappa constant
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KYNU kynureninase
MMP7 matrix metallopeptidase 7
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SH3YL1 SH3 and SYLF domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TGFBI transforming growth factor, beta-induced, 68kDa
UPK1B uroplakin 1B

decreased expression

Symbol Name
ALB albumin
ANPEP alanyl (membrane) aminopeptidase
ANXA3 annexin A3
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CD24 CD24 molecule
COL13A1 collagen, type XIII, alpha 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
EVL Enah/Vasp-like
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FHL2 four and a half LIM domains 2
GREB1 growth regulation by estrogen in breast cancer 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOMER2 homer scaffolding protein 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MME membrane metallo-endopeptidase
MSLN mesothelin
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PDGFC platelet derived growth factor C
PDZK1 PDZ domain containing 1
PODXL podocalyxin-like
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
REG1A regenerating islet-derived 1 alpha
RGS1 regulator of G-protein signaling 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNX10 sorting nexin 10
TPD52 tumor protein D52
TUBB2A tubulin, beta 2A class IIa