BRD-K39187410_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

33 genes differentially expressed following the BRD-K39187410_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
FHL1 four and a half LIM domains 1
GAS1 growth arrest-specific 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
HSPA1A heat shock 70kDa protein 1A
KRT18 keratin 18, type I
KRT7 keratin 7, type II
MKNK2 MAP kinase interacting serine/threonine kinase 2
OXTR oxytocin receptor
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
SRSF6 serine/arginine-rich splicing factor 6
TDO2 tryptophan 2,3-dioxygenase
TP53 tumor protein p53

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ARID4B AT rich interactive domain 4B (RBP1-like)
CCL20 chemokine (C-C motif) ligand 20
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNIH4 cornichon family AMPA receptor auxiliary protein 4
DOCK4 dedicator of cytokinesis 4
HMGA2 high mobility group AT-hook 2
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NVL nuclear VCP-like
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
THBS1 thrombospondin 1
TOX3 TOX high mobility group box family member 3
ZMIZ1 zinc finger, MIZ-type containing 1