BRD-K38756014_G-201_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

91 genes differentially expressed following the BRD-K38756014_G-201_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANOS1 anosmin 1
BTBD3 BTB (POZ) domain containing 3
CDK19 cyclin-dependent kinase 19
CP ceruloplasmin (ferroxidase)
CST7 cystatin F (leukocystatin)
F12 coagulation factor XII (Hageman factor)
FBN2 fibrillin 2
FKBP1A FK506 binding protein 1A, 12kDa
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTA4 glutathione S-transferase alpha 4
GYPC glycophorin C (Gerbich blood group)
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV3-19 immunoglobulin lambda variable 3-19
KANK1 KN motif and ankyrin repeat domains 1
KRT16 keratin 16, type I
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
MET MET proto-oncogene, receptor tyrosine kinase
MMP7 matrix metallopeptidase 7
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PERP PERP, TP53 apoptosis effector
RAD51C RAD51 paralog C
RGCC regulator of cell cycle
RNF167 ring finger protein 167
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SOX17 SRY (sex determining region Y)-box 17
SRGN serglycin
STX1A syntaxin 1A (brain)
TGM2 transglutaminase 2
TNC tenascin C
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ABAT 4-aminobutyrate aminotransferase
ADD3 adducin 3 (gamma)
ANK2 ankyrin 2, neuronal
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BARD1 BRCA1 associated RING domain 1
BEX4 brain expressed, X-linked 4
CFD complement factor D (adipsin)
CIAPIN1 cytokine induced apoptosis inhibitor 1
COASY CoA synthase
COL1A1 collagen, type I, alpha 1
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
CPE carboxypeptidase E
CRISP3 cysteine-rich secretory protein 3
CTSK cathepsin K
CYBA cytochrome b-245, alpha polypeptide
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DCN decorin
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF4A1 eukaryotic translation initiation factor 4A1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FBP1 fructose-1,6-bisphosphatase 1
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
IFI44 interferon-induced protein 44
IL7R interleukin 7 receptor
ISG15 ISG15 ubiquitin-like modifier
ITM2A integral membrane protein 2A
MAGED2 melanoma antigen family D2
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPT microtubule-associated protein tau
METTL7A methyltransferase like 7A
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
NELL2 NEL-like 2 (chicken)
NOLC1 nucleolar and coiled-body phosphoprotein 1
PEG10 paternally expressed 10
PSPH phosphoserine phosphatase
RRAGD Ras-related GTP binding D
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK1 serine peptidase inhibitor, Kazal type 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNS1 tensin 1
ZBTB18 zinc finger and BTB domain containing 18