BRD-K38634661_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K38634661_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
ARG2 arginase 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTG3 BTG family, member 3
CAST calpastatin
CAV1 caveolin 1, caveolae protein, 22kDa
CCND2 cyclin D2
CD24 CD24 molecule
CD9 CD9 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLU clusterin
COL14A1 collagen, type XIV, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
EPCAM epithelial cell adhesion molecule
EPHA4 EPH receptor A4
FHL1 four and a half LIM domains 1
GBE1 glucan (1,4-alpha-), branching enzyme 1
GDF15 growth differentiation factor 15
GMPR guanosine monophosphate reductase
HK2 hexokinase 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
KRT19 keratin 19, type I
KRT8 keratin 8, type II
LOC100505650 uncharacterized LOC100505650
LUM lumican
MMP7 matrix metallopeptidase 7
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
OXSR1 oxidative stress responsive 1
PAGE4 P antigen family, member 4 (prostate associated)
PAM peptidylglycine alpha-amidating monooxygenase
PCP4 Purkinje cell protein 4
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
SFRP4 secreted frizzled-related protein 4
SPARCL1 SPARC-like 1 (hevin)
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFF3 trefoil factor 3 (intestinal)
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNNC1 troponin C type 1 (slow)
TPD52L1 tumor protein D52-like 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
C6ORF62 chromosome 6 open reading frame 62
FOLR1 folate receptor 1 (adult)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HOXA5 homeobox A5
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6ST interleukin 6 signal transducer
IQCG IQ motif containing G
KRT6B keratin 6B, type II
SLC25A46 solute carrier family 25, member 46
TBC1D4 TBC1 domain family, member 4
TRA2B transformer 2 beta homolog (Drosophila)
TUBB2A tubulin, beta 2A class IIa
UGDH UDP-glucose 6-dehydrogenase
ZFAND5 zinc finger, AN1-type domain 5