BRD-K38625260_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K38625260_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
ADM adrenomedullin
ALCAM activated leukocyte cell adhesion molecule
APLP2 amyloid beta (A4) precursor-like protein 2
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BASP1 brain abundant, membrane attached signal protein 1
BTBD3 BTB (POZ) domain containing 3
CA2 carbonic anhydrase II
CCL20 chemokine (C-C motif) ligand 20
CD1E CD1e molecule
CDA cytidine deaminase
CLIC5 chloride intracellular channel 5
COCH cochlin
CPM carboxypeptidase M
CYTL1 cytokine-like 1
DUSP4 dual specificity phosphatase 4
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5A eukaryotic translation initiation factor 5A
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOXF1 forkhead box F1
GPX3 glutathione peroxidase 3
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
JAG1 jagged 1
KDM5D lysine (K)-specific demethylase 5D
KLF4 Kruppel-like factor 4 (gut)
LAMP3 lysosomal-associated membrane protein 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOA monoamine oxidase A
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDGFA platelet-derived growth factor alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PLA1A phospholipase A1 member A
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SH2B3 SH2B adaptor protein 3
SYT1 synaptotagmin I

decreased expression

Symbol Name
CALML5 calmodulin-like 5
CCNF cyclin F
COG2 component of oligomeric golgi complex 2
CXCL5 chemokine (C-X-C motif) ligand 5
DCK deoxycytidine kinase
FAM57A family with sequence similarity 57, member A
GTPBP8 GTP-binding protein 8 (putative)
HAT1 histone acetyltransferase 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HOOK2 hook microtubule-tethering protein 2
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
IL17RB interleukin 17 receptor B
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
LRRC16A leucine rich repeat containing 16A
LYZ lysozyme
MAN1C1 mannosidase, alpha, class 1C, member 1
METRN meteorin, glial cell differentiation regulator
MGP matrix Gla protein
MT1F metallothionein 1F
MT1X metallothionein 1X
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDGFRL platelet-derived growth factor receptor-like
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRR15L proline rich 15-like
PTGES prostaglandin E synthase
PWP1 PWP1 homolog (S. cerevisiae)
RPL10 ribosomal protein L10
RSRP1 arginine/serine-rich protein 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SMAD1 SMAD family member 1
SRSF6 serine/arginine-rich splicing factor 6
STAT1 signal transducer and activator of transcription 1, 91kDa
TGFB3 transforming growth factor, beta 3
TMEM185B transmembrane protein 185B