BRD-K38340366_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

113 genes differentially expressed following the BRD-K38340366_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
ANGPTL2 angiopoietin-like 2
ANKRD10 ankyrin repeat domain 10
ASS1 argininosuccinate synthase 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
CA1 carbonic anhydrase I
CA2 carbonic anhydrase II
CALML4 calmodulin-like 4
CDH17 cadherin 17, LI cadherin (liver-intestine)
CXCL14 chemokine (C-X-C motif) ligand 14
DPYSL2 dihydropyrimidinase-like 2
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FHL1 four and a half LIM domains 1
GAL galanin/GMAP prepropeptide
GCH1 GTP cyclohydrolase 1
GREM1 gremlin 1, DAN family BMP antagonist
GSDMB gasdermin B
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HIST2H2BE histone cluster 2, H2be
IGFBP5 insulin-like growth factor binding protein 5
JUN jun proto-oncogene
KIAA0907 KIAA0907
LOX lysyl oxidase
LOXL2 lysyl oxidase-like 2
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase
MT1E metallothionein 1E
MT1X metallothionein 1X
MTCL1 microtubule crosslinking factor 1
MXRA7 matrix-remodelling associated 7
NT5E 5'-nucleotidase, ecto (CD73)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDE4DIP phosphodiesterase 4D interacting protein
PRUNE2 prune homolog 2 (Drosophila)
RAP1GAP2 RAP1 GTPase activating protein 2
RCAN1 regulator of calcineurin 1
RPL31 ribosomal protein L31
RSL1D1 ribosomal L1 domain containing 1
S100A6 S100 calcium binding protein A6
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG2 secretogranin II
SCG5 secretogranin V
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAI2 snail family zinc finger 2
SPON1 spondin 1, extracellular matrix protein
SPTSSA serine palmitoyltransferase, small subunit A
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMOD1 tropomodulin 1
TNNT1 troponin T type 1 (skeletal, slow)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
BASP1 brain abundant, membrane attached signal protein 1
CD58 CD58 molecule
CEP170 centrosomal protein 170kDa
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COL3A1 collagen, type III, alpha 1
CYB561 cytochrome b561
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAPK1 death-associated protein kinase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFHD1 EF-hand domain family, member D1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FAM63A family with sequence similarity 63, member A
GDF15 growth differentiation factor 15
GPRC5A G protein-coupled receptor, class C, group 5, member A
HN1 hematological and neurological expressed 1
HSPB8 heat shock 22kDa protein 8
IFITM3 interferon induced transmembrane protein 3
INTS3 integrator complex subunit 3
KIAA1033 KIAA1033
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT7 keratin 7, type II
KYNU kynureninase
LAPTM4B lysosomal protein transmembrane 4 beta
MGP matrix Gla protein
NFIB nuclear factor I/B
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
PCM1 pericentriolar material 1
PMM2 phosphomannomutase 2
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PSIP1 PC4 and SFRS1 interacting protein 1
QKI QKI, KH domain containing, RNA binding
S100P S100 calcium binding protein P
SCYL3 SCY1-like 3 (S. cerevisiae)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SNX10 sorting nexin 10
SPATS2L spermatogenesis associated, serine-rich 2-like
STAMBP STAM binding protein
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TACSTD2 tumor-associated calcium signal transducer 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN8 tetraspanin 8
UPK1B uroplakin 1B
VAMP8 vesicle-associated membrane protein 8
WSB1 WD repeat and SOCS box containing 1
ZNF586 zinc finger protein 586