BRD-K38144109_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K38144109_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
BAG3 BCL2-associated athanogene 3
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
FADS1 fatty acid desaturase 1
FOLR1 folate receptor 1 (adult)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
LDLR low density lipoprotein receptor
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMO1 methylsterol monooxygenase 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SRPX sushi-repeat containing protein, X-linked
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
CLCA4 chloride channel accessory 4
COL4A5 collagen, type IV, alpha 5
EGLN3 egl-9 family hypoxia-inducible factor 3
IFITM1 interferon induced transmembrane protein 1
MAN1A1 mannosidase, alpha, class 1A, member 1
PPOX protoporphyrinogen oxidase
RGS5 regulator of G-protein signaling 5
TRPS1 trichorhinophalangeal syndrome I
XIST X inactive specific transcript (non-protein coding)
ZNF395 zinc finger protein 395