BRD-K37865504_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K37865504_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AIM2 absent in melanoma 2
BAG3 BCL2-associated athanogene 3
CD24 CD24 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CXCL14 chemokine (C-X-C motif) ligand 14
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP14 dual specificity phosphatase 14
F2RL1 coagulation factor II (thrombin) receptor-like 1
FHL2 four and a half LIM domains 2
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSPA1A heat shock 70kDa protein 1A
IFI27 interferon, alpha-inducible protein 27
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KRT6A keratin 6A, type II
LDLR low density lipoprotein receptor
MSMO1 methylsterol monooxygenase 1
PPARD peroxisome proliferator-activated receptor delta
RRAD Ras-related associated with diabetes
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SEC14L1 SEC14-like 1 (S. cerevisiae)
SFN stratifin
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SPRR2B small proline-rich protein 2B
THBS1 thrombospondin 1
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
C14ORF132 chromosome 14 open reading frame 132
CRISP3 cysteine-rich secretory protein 3
EMP2 epithelial membrane protein 2
GATA2 GATA binding protein 2
GPX2 glutathione peroxidase 2
HOXA10 homeobox A10
MAOA monoamine oxidase A
MMD monocyte to macrophage differentiation-associated
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PPARG peroxisome proliferator-activated receptor gamma
PRAME preferentially expressed antigen in melanoma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGS2 regulator of G-protein signaling 2
SRGN serglycin
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
WNT5A wingless-type MMTV integration site family, member 5A