BRD-K37764012_PF-3758309_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K37764012_PF-3758309_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DSP desmoplakin
FHL2 four and a half LIM domains 2
FILIP1L filamin A interacting protein 1-like
H2BFS H2B histone family, member S (pseudogene)
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HSPA1A heat shock 70kDa protein 1A
KRT18 keratin 18, type I
SDC4 syndecan 4
SPINK1 serine peptidase inhibitor, Kazal type 1
TGFA transforming growth factor, alpha
TNFRSF21 tumor necrosis factor receptor superfamily, member 21

decreased expression

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
IGKC immunoglobulin kappa constant
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
ITM2A integral membrane protein 2A
LMO4 LIM domain only 4
MME membrane metallo-endopeptidase
PHGDH phosphoglycerate dehydrogenase
PLIN2 perilipin 2
PSAT1 phosphoserine aminotransferase 1
PYCR1 pyrroline-5-carboxylate reductase 1
RGS1 regulator of G-protein signaling 1
RNASE4 ribonuclease, RNase A family, 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STC2 stanniocalcin 2
TCF4 transcription factor 4
TNC tenascin C
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1