BRD-K37691127_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

64 genes differentially expressed following the BRD-K37691127_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK4 adenylate kinase 4
ALDOC aldolase C, fructose-bisphosphate
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CLIC4 chloride intracellular channel 4
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
EXPH5 exophilin 5
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM162A family with sequence similarity 162, member A
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HILPDA hypoxia inducible lipid droplet-associated
HSPA13 heat shock protein 70kDa family, member 13
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGL immunoglobulin lambda locus
INHBA inhibin, beta A
ISG20 interferon stimulated exonuclease gene 20kDa
KDM3A lysine (K)-specific demethylase 3A
KRT23 keratin 23, type I
MX1 MX dynamin-like GTPase 1
MXI1 MAX interactor 1, dimerization protein
NDRG1 N-myc downstream regulated 1
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PEG3 paternally expressed 3
PGK1 phosphoglycerate kinase 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
SCGB2A2 secretoglobin, family 2A, member 2
SEPP1 selenoprotein P, plasma, 1
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SULF1 sulfatase 1
TPD52 tumor protein D52
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AURKA aurora kinase A
BAG3 BCL2-associated athanogene 3
CBR3 carbonyl reductase 3
CCNB2 cyclin B2
CCNF cyclin F
CDKN3 cyclin-dependent kinase inhibitor 3
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EXOSC4 exosome component 4
FOLR1 folate receptor 1 (adult)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HLTF helicase-like transcription factor
HSPA1A heat shock 70kDa protein 1A
HSPA8 heat shock 70kDa protein 8
KIF20A kinesin family member 20A
LDLR low density lipoprotein receptor
MOK MOK protein kinase
PLK1 polo-like kinase 1
PNMA1 paraneoplastic Ma antigen 1
SLIRP SRA stem-loop interacting RNA binding protein
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM2 transmembrane protein 2
TOP2A topoisomerase (DNA) II alpha 170kDa
UBE2S ubiquitin-conjugating enzyme E2S