BRD-K37687095_AZD-8330_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K37687095_AZD-8330_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ASS1 argininosuccinate synthase 1
CA12 carbonic anhydrase XII
CEMIP cell migration inducing protein, hyaluronan binding
GPX3 glutathione peroxidase 3
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
MAOA monoamine oxidase A
NARFL nuclear prelamin A recognition factor-like
NUSAP1 nucleolar and spindle associated protein 1
PRSS21 protease, serine, 21 (testisin)
S100A8 S100 calcium binding protein A8

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
AMIGO2 adhesion molecule with Ig-like domain 2
AREG amphiregulin
ASCL1 achaete-scute family bHLH transcription factor 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BPHL biphenyl hydrolase-like (serine hydrolase)
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CFLAR CASP8 and FADD-like apoptosis regulator
CHN1 chimerin 1
CXCR4 chemokine (C-X-C motif) receptor 4
DLK1 delta-like 1 homolog (Drosophila)
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EFNB2 ephrin-B2
EGR3 early growth response 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
ETV1 ets variant 1
ETV5 ets variant 5
FBP1 fructose-1,6-bisphosphatase 1
FOSL1 FOS-like antigen 1
FOXC1 forkhead box C1
FRZB frizzled-related protein
GDF15 growth differentiation factor 15
GPM6B glycoprotein M6B
GPX1 glutathione peroxidase 1
GUSBP3 glucuronidase, beta pseudogene 3
HBEGF heparin-binding EGF-like growth factor
HOPX HOP homeobox
HOXA10 homeobox A10
HOXA5 homeobox A5
HOXB2 homeobox B2
IER3 immediate early response 3
IGFBP7 insulin-like growth factor binding protein 7
ITGA6 integrin, alpha 6
LAMB3 laminin, beta 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP1B microtubule-associated protein 1B
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAV3 neuron navigator 3
NPIPB3 nuclear pore complex interacting protein family, member B3
NPTX2 neuronal pentraxin II
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PDE4B phosphodiesterase 4B, cAMP-specific
PDE4C phosphodiesterase 4C, cAMP-specific
PERP PERP, TP53 apoptosis effector
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RND3 Rho family GTPase 3
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFRP1 secreted frizzled-related protein 1
SFTPA2 surfactant protein A2
SIK1 salt-inducible kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
SRPX sushi-repeat containing protein, X-linked
STX1A syntaxin 1A (brain)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TOX3 TOX high mobility group box family member 3
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa
USP34 ubiquitin specific peptidase 34
ZNF160 zinc finger protein 160
ZNF721 zinc finger protein 721