BRD-K37687095_AZD-8330_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

102 genes differentially expressed following the BRD-K37687095_AZD-8330_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADAM12 ADAM metallopeptidase domain 12
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ANKRD10 ankyrin repeat domain 10
APOD apolipoprotein D
ASS1 argininosuccinate synthase 1
BAMBI BMP and activin membrane-bound inhibitor
C1R complement component 1, r subcomponent
CDK14 cyclin-dependent kinase 14
CFB complement factor B
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DSP desmoplakin
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLS glutaminase
GPX3 glutathione peroxidase 3
GSTT1 glutathione S-transferase theta 1
HOPX HOP homeobox
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IL1R1 interleukin 1 receptor, type I
KRT7 keratin 7, type II
LRRC1 leucine rich repeat containing 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MAN2A1 mannosidase, alpha, class 2A, member 1
METTL7A methyltransferase like 7A
MTSS1 metastasis suppressor 1
MXI1 MAX interactor 1, dimerization protein
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM3 PDZ and LIM domain 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLEKHA5 pleckstrin homology domain containing, family A member 5
PTGIS prostaglandin I2 (prostacyclin) synthase
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RGS5 regulator of G-protein signaling 5
RHOBTB3 Rho-related BTB domain containing 3
SCGB1D2 secretoglobin, family 1D, member 2
SOX4 SRY (sex determining region Y)-box 4
SPON2 spondin 2, extracellular matrix protein
STOM stomatin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR3 transforming growth factor, beta receptor III
VGLL1 vestigial-like family member 1
YBX3 Y box binding protein 3
ZBTB16 zinc finger and BTB domain containing 16
ZHX2 zinc fingers and homeoboxes 2

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
APOE apolipoprotein E
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARL4C ADP-ribosylation factor-like 4C
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP6 dual specificity phosphatase 6
EGR2 early growth response 2
EMP1 epithelial membrane protein 1
EPHA2 EPH receptor A2
FOSL1 FOS-like antigen 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPNMB glycoprotein (transmembrane) nmb
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
IER3 immediate early response 3
JUN jun proto-oncogene
KCTD12 potassium channel tetramerization domain containing 12
KPNA4 karyopherin alpha 4 (importin alpha 3)
KYNU kynureninase
LEFTY1 left-right determination factor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NELL2 NEL-like 2 (chicken)
PEX11A peroxisomal biogenesis factor 11 alpha
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAUR plasminogen activator, urokinase receptor
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POPDC3 popeye domain containing 3
PRNP prion protein
RTN1 reticulon 1
SAMHD1 SAM domain and HD domain 1
SGK1 serum/glucocorticoid regulated kinase 1
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
SRGN serglycin
STX1A syntaxin 1A (brain)
TFF3 trefoil factor 3 (intestinal)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TLR4 toll-like receptor 4
TM4SF1 transmembrane 4 L six family member 1
ZYX zyxin