BRD-K37687095_AZD-8330_BT20_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K37687095_AZD-8330_BT20_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ADIRF adipogenesis regulatory factor
BAMBI BMP and activin membrane-bound inhibitor
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CCL5 chemokine (C-C motif) ligand 5
CD40 CD40 molecule, TNF receptor superfamily member 5
CD69 CD69 molecule
CXADR coxsackie virus and adenovirus receptor
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
EPS8 epidermal growth factor receptor pathway substrate 8
FAS Fas cell surface death receptor
GSN gelsolin
IGFBP5 insulin-like growth factor binding protein 5
IGHM immunoglobulin heavy constant mu
LMO3 LIM domain only 3 (rhombotin-like 2)
MAOA monoamine oxidase A
METTL7A methyltransferase like 7A
MTSS1 metastasis suppressor 1
PBX3 pre-B-cell leukemia homeobox 3
PEG10 paternally expressed 10
PROS1 protein S (alpha)
RAD23B RAD23 homolog B (S. cerevisiae)
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A4 S100 calcium binding protein A4
SATB1 SATB homeobox 1
SDC2 syndecan 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TP53I3 tumor protein p53 inducible protein 3

decreased expression

Symbol Name
ARL4C ADP-ribosylation factor-like 4C
AXL AXL receptor tyrosine kinase
BAD BCL2-associated agonist of cell death
CIAPIN1 cytokine induced apoptosis inhibitor 1
COL3A1 collagen, type III, alpha 1
DUSP4 dual specificity phosphatase 4
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHA2 EPH receptor A2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FOSL1 FOS-like antigen 1
GDF15 growth differentiation factor 15
GRB7 growth factor receptor-bound protein 7
HBEGF heparin-binding EGF-like growth factor
HOXB2 homeobox B2
IER3 immediate early response 3
IGFBP6 insulin-like growth factor binding protein 6
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SMAD3 SMAD family member 3
SOX9 SRY (sex determining region Y)-box 9
SPRED2 sprouty-related, EVH1 domain containing 2
SRGN serglycin
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TRIB2 tribbles pseudokinase 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)