BRD-K37687095_AZD-8330_BT20_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K37687095_AZD-8330_BT20_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRL2 adhesion G protein-coupled receptor L2
AMACR alpha-methylacyl-CoA racemase
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFB complement factor B
CLU clusterin
CSRP2 cysteine and glycine-rich protein 2
DLK1 delta-like 1 homolog (Drosophila)
EVL Enah/Vasp-like
FMOD fibromodulin
GLUL glutamate-ammonia ligase
HIST1H2AE histone cluster 1, H2ae
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
KIAA0485 uncharacterized LOC57235
METTL7A methyltransferase like 7A
MID1 midline 1
NUPR1 nuclear protein, transcriptional regulator, 1
PTGIS prostaglandin I2 (prostacyclin) synthase
TCF4 transcription factor 4
TMEM100 transmembrane protein 100

decreased expression

Symbol Name
ARID4B AT rich interactive domain 4B (RBP1-like)
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC42 cell division cycle 42
EIF5A eukaryotic translation initiation factor 5A
ENOPH1 enolase-phosphatase 1
EZR ezrin
F2RL1 coagulation factor II (thrombin) receptor-like 1
ITGA6 integrin, alpha 6
NT5E 5'-nucleotidase, ecto (CD73)
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
RFC2 replication factor C (activator 1) 2, 40kDa
UBE2S ubiquitin-conjugating enzyme E2S