BRD-K37456065_VU0365114-2_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

48 genes differentially expressed following the BRD-K37456065_VU0365114-2_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANXA3 annexin A3
CBR3 carbonyl reductase 3
CBX1 chromobox homolog 1
CCNA2 cyclin A2
CCNB2 cyclin B2
CD24 CD24 molecule
CDC25B cell division cycle 25B
CENPA centromere protein A
CENPF centromere protein F, 350/400kDa
CRYAB crystallin, alpha B
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EPCAM epithelial cell adhesion molecule
FXYD2 FXYD domain containing ion transport regulator 2
HOXA10 homeobox A10
JADE2 jade family PHD finger 2
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
KTN1 kinectin 1 (kinesin receptor)
MARCKS myristoylated alanine-rich protein kinase C substrate
NDC80 NDC80 kinetochore complex component
NUSAP1 nucleolar and spindle associated protein 1
PLA2G16 phospholipase A2, group XVI
PLK1 polo-like kinase 1
PROM1 prominin 1
RBPMS RNA binding protein with multiple splicing
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SH3BP4 SH3-domain binding protein 4
SNX11 sorting nexin 11
TBL1X transducin (beta)-like 1X-linked
UBE3C ubiquitin protein ligase E3C
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C10ORF10 chromosome 10 open reading frame 10
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
EFNB2 ephrin-B2
FABP7 fatty acid binding protein 7, brain
GRIA2 glutamate receptor, ionotropic, AMPA 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MPO myeloperoxidase
PTPRE protein tyrosine phosphatase, receptor type, E
S100A8 S100 calcium binding protein A8
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
TFF3 trefoil factor 3 (intestinal)
TSPAN7 tetraspanin 7