BRD-K37312348_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K37312348_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ANXA4 annexin A4
BAD BCL2-associated agonist of cell death
BEX4 brain expressed, X-linked 4
C2CD2 C2 calcium-dependent domain containing 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNPY3 canopy FGF signaling regulator 3
DDIT4 DNA-damage-inducible transcript 4
DUSP5 dual specificity phosphatase 5
ENO2 enolase 2 (gamma, neuronal)
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
GDF15 growth differentiation factor 15
HCAR3 hydroxycarboxylic acid receptor 3
HOXA10 homeobox A10
MTA1 metastasis associated 1
PDE8B phosphodiesterase 8B
PDLIM1 PDZ and LIM domain 1
PIH1D1 PIH1 domain containing 1
PRKCB protein kinase C, beta
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP2C RAP2C, member of RAS oncogene family
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM45A transmembrane protein 45A
TNFAIP8 tumor necrosis factor, alpha-induced protein 8

decreased expression

Symbol Name
ADI1 acireductone dioxygenase 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEMIP cell migration inducing protein, hyaluronan binding
COL10A1 collagen, type X, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
DCN decorin
DENND1B DENN/MADD domain containing 1B
DLC1 DLC1 Rho GTPase activating protein
FAM46A family with sequence similarity 46, member A
GPRC5A G protein-coupled receptor, class C, group 5, member A
GSTA1 glutathione S-transferase alpha 1
GTPBP8 GTP-binding protein 8 (putative)
HES1 hes family bHLH transcription factor 1
IGF1R insulin-like growth factor 1 receptor
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INTS3 integrator complex subunit 3
KIF20A kinesin family member 20A
MAMLD1 mastermind-like domain containing 1
MAP7 microtubule-associated protein 7
MT1X metallothionein 1X
MTUS1 microtubule associated tumor suppressor 1
NFIB nuclear factor I/B
NR4A2 nuclear receptor subfamily 4, group A, member 2
PHACTR2 phosphatase and actin regulator 2
PLAGL1 pleiomorphic adenoma gene-like 1
PMP22 peripheral myelin protein 22
POSTN periostin, osteoblast specific factor
RHOBTB3 Rho-related BTB domain containing 3
S100P S100 calcium binding protein P
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFTPB surfactant protein B
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SOBP sine oculis binding protein homolog (Drosophila)
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPINK1 serine peptidase inhibitor, Kazal type 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR3 transforming growth factor, beta receptor III