BRD-K37206356_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K37206356_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADORA2B adenosine A2b receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AXL AXL receptor tyrosine kinase
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC85B coiled-coil domain containing 85B
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
DAPK1 death-associated protein kinase 1
DEFB1 defensin, beta 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EREG epiregulin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM3C family with sequence similarity 3, member C
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FKBP11 FK506 binding protein 11, 19 kDa
FOSL1 FOS-like antigen 1
FSD1 fibronectin type III and SPRY domain containing 1
GNB5 guanine nucleotide binding protein (G protein), beta 5
GPX3 glutathione peroxidase 3
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
NISCH nischarin
PAEP progestagen-associated endometrial protein
PUS7 pseudouridylate synthase 7 (putative)
S100A2 S100 calcium binding protein A2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
TKT transketolase
TSKU tsukushi, small leucine rich proteoglycan

decreased expression

Symbol Name
ANXA9 annexin A9
C7 complement component 7
CFD complement factor D (adipsin)
CIRBP cold inducible RNA binding protein
CRABP2 cellular retinoic acid binding protein 2
CRIP2 cysteine-rich protein 2
CSRP1 cysteine and glycine-rich protein 1
ERI2 ERI1 exoribonuclease family member 2
ESR1 estrogen receptor 1
EVL Enah/Vasp-like
FAM63A family with sequence similarity 63, member A
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GHR growth hormone receptor
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BE histone cluster 1, H2be
HIST1H2BF histone cluster 1, H2bf
HIST1H2BG histone cluster 1, H2bg
HIST1H2BH histone cluster 1, H2bh
IFI44 interferon-induced protein 44
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
INSIG1 insulin induced gene 1
ISG15 ISG15 ubiquitin-like modifier
LGALS3 lectin, galactoside-binding, soluble, 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MGP matrix Gla protein
MUC1 mucin 1, cell surface associated
NFIB nuclear factor I/B
NPY1R neuropeptide Y receptor Y1
PEX11A peroxisomal biogenesis factor 11 alpha
PRR15L proline rich 15-like
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
TFF3 trefoil factor 3 (intestinal)
TMEM135 transmembrane protein 135
TOB1 transducer of ERBB2, 1
TSC22D3 TSC22 domain family, member 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)