BRD-K37150847_methyl (3-phenyl-1H-indazol-1-yl)acetate BRD-K37150847_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

79 genes differentially expressed following the BRD-K37150847_methyl (3-phenyl-1H-indazol-1-yl)acetate BRD-K37150847_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADRB2 adrenoceptor beta 2, surface
ALOX5 arachidonate 5-lipoxygenase
ANO1 anoctamin 1, calcium activated chloride channel
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
BHLHE41 basic helix-loop-helix family, member e41
BTBD3 BTB (POZ) domain containing 3
C2CD2 C2 calcium-dependent domain containing 2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLEC2B C-type lectin domain family 2, member B
COL1A2 collagen, type I, alpha 2
CP ceruloplasmin (ferroxidase)
CPM carboxypeptidase M
FGG fibrinogen gamma chain
GBP2 guanylate binding protein 2, interferon-inducible
GLUL glutamate-ammonia ligase
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HBB hemoglobin, beta
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IFI16 interferon, gamma-inducible protein 16
IGKV4-1 immunoglobulin kappa variable 4-1
LAMP3 lysosomal-associated membrane protein 3
LDHB lactate dehydrogenase B
MET MET proto-oncogene, receptor tyrosine kinase
MTSS1 metastasis suppressor 1
MUC5B mucin 5B, oligomeric mucus/gel-forming
NDP Norrie disease (pseudoglioma)
NEFL neurofilament, light polypeptide
PCP4 Purkinje cell protein 4
PLA1A phospholipase A1 member A
PTGIS prostaglandin I2 (prostacyclin) synthase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS2 regulator of G-protein signaling 2
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SPAG4 sperm associated antigen 4
TLR2 toll-like receptor 2
TSPAN5 tetraspanin 5
TSPAN8 tetraspanin 8
TTC3 tetratricopeptide repeat domain 3
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VSIG4 V-set and immunoglobulin domain containing 4

decreased expression

Symbol Name
BCAS3 breast carcinoma amplified sequence 3
BID BH3 interacting domain death agonist
CALR calreticulin
CCDC86 coiled-coil domain containing 86
CDCA4 cell division cycle associated 4
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHGB chromogranin B
CLTB clathrin, light chain B
COG2 component of oligomeric golgi complex 2
CYB561 cytochrome b561
ELF1 E74-like factor 1 (ets domain transcription factor)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBXL12 F-box and leucine-rich repeat protein 12
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
KRT6B keratin 6B, type II
LGALS1 lectin, galactoside-binding, soluble, 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PWP1 PWP1 homolog (S. cerevisiae)
PYCARD PYD and CARD domain containing
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TUBB6 tubulin, beta 6 class V
VEGFA vascular endothelial growth factor A
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
ZMYM2 zinc finger, MYM-type 2