BRD-K37043259_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

138 genes differentially expressed following the BRD-K37043259_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ANXA2 annexin A2
ANXA6 annexin A6
ARG2 arginase 2
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG3 BTG family, member 3
C3ORF14 chromosome 3 open reading frame 14
CAST calpastatin
CCND2 cyclin D2
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFB complement factor B
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPE carboxypeptidase E
CRABP2 cellular retinoic acid binding protein 2
CXADR coxsackie virus and adenovirus receptor
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
EDNRB endothelin receptor type B
EIF5A eukaryotic translation initiation factor 5A
FAIM Fas apoptotic inhibitory molecule
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
FHL1 four and a half LIM domains 1
FXYD5 FXYD domain containing ion transport regulator 5
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GLRX glutaredoxin (thioltransferase)
HMOX1 heme oxygenase 1
HOXB2 homeobox B2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IER3 immediate early response 3
ITGB7 integrin, beta 7
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT23 keratin 23, type I
LGALS1 lectin, galactoside-binding, soluble, 1
LIMCH1 LIM and calponin homology domains 1
LMO3 LIM domain only 3 (rhombotin-like 2)
LTB lymphotoxin beta (TNF superfamily, member 3)
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
MBNL2 muscleblind-like splicing regulator 2
MCAM melanoma cell adhesion molecule
MEIS2 Meis homeobox 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MMD monocyte to macrophage differentiation-associated
MMP7 matrix metallopeptidase 7
MSN moesin
MT1M metallothionein 1M
NEBL nebulette
NELL2 NEL-like 2 (chicken)
NPTX2 neuronal pentraxin II
NT5E 5'-nucleotidase, ecto (CD73)
NTS neurotensin
OLFM4 olfactomedin 4
OSBPL10 oxysterol binding protein-like 10
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCLO piccolo presynaptic cytomatrix protein
PCSK1 proprotein convertase subtilisin/kexin type 1
PDE4B phosphodiesterase 4B, cAMP-specific
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLIN2 perilipin 2
PLS1 plastin 1
PRAME preferentially expressed antigen in melanoma
PRR15L proline rich 15-like
QPCT glutaminyl-peptide cyclotransferase
RAB29 RAB29, member RAS oncogene family
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RFX5 regulatory factor X, 5 (influences HLA class II expression)
RGCC regulator of cell cycle
RND3 Rho family GTPase 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RTN2 reticulon 2
SCG2 secretogranin II
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
STON1 stonin 1
SV2A synaptic vesicle glycoprotein 2A
SYNM synemin, intermediate filament protein
SYT1 synaptotagmin I
TAC1 tachykinin, precursor 1
TFPI2 tissue factor pathway inhibitor 2
THBS2 thrombospondin 2
TM4SF1 transmembrane 4 L six family member 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPD52 tumor protein D52
TPM2 tropomyosin 2 (beta)
TRIM2 tripartite motif containing 2
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VIM vimentin
WIF1 WNT inhibitory factor 1
WWTR1 WW domain containing transcription regulator 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AK4 adenylate kinase 4
BLCAP bladder cancer associated protein
CDA cytidine deaminase
COL6A1 collagen, type VI, alpha 1
CST3 cystatin C
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
EFNB2 ephrin-B2
GRWD1 glutamate-rich WD repeat containing 1
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IL1R2 interleukin 1 receptor, type II
IL1RN interleukin 1 receptor antagonist
KAZN kazrin, periplakin interacting protein
KIAA1551 KIAA1551
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARCKS myristoylated alanine-rich protein kinase C substrate
NUP98 nucleoporin 98kDa
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDGFA platelet-derived growth factor alpha polypeptide
PLEC plectin
PLXNA1 plexin A1
PPIF peptidylprolyl isomerase F
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RXRA retinoid X receptor, alpha
TBX2 T-box 2
TNPO1 transportin 1