BRD-K36740062_GSK-1070916_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K36740062_GSK-1070916_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAM10 ADAM metallopeptidase domain 10
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
AUTS2 autism susceptibility candidate 2
BPHL biphenyl hydrolase-like (serine hydrolase)
CLU clusterin
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GUSBP3 glucuronidase, beta pseudogene 3
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HOXB6 homeobox B6
HOXC6 homeobox C6
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INTS3 integrator complex subunit 3
ITM2A integral membrane protein 2A
KLK11 kallikrein-related peptidase 11
LAMP5 lysosomal-associated membrane protein family, member 5
MARCKS myristoylated alanine-rich protein kinase C substrate
MYRF myelin regulatory factor
NTS neurotensin
PEG10 paternally expressed 10
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
REEP5 receptor accessory protein 5
SERINC5 serine incorporator 5
SPRY2 sprouty homolog 2 (Drosophila)
TFPI2 tissue factor pathway inhibitor 2
TGFBR3 transforming growth factor, beta receptor III
TM9SF3 transmembrane 9 superfamily member 3
TOP2A topoisomerase (DNA) II alpha 170kDa

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
CA12 carbonic anhydrase XII
CCL20 chemokine (C-C motif) ligand 20
CEMIP cell migration inducing protein, hyaluronan binding
COL8A2 collagen, type VIII, alpha 2
CPQ carboxypeptidase Q
CRYAB crystallin, alpha B
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
FABP7 fatty acid binding protein 7, brain
FAM69A family with sequence similarity 69, member A
GBP1 guanylate binding protein 1, interferon-inducible
IGFBP5 insulin-like growth factor binding protein 5
IPO13 importin 13
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
MFAP5 microfibrillar associated protein 5
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MT1F metallothionein 1F
MT1H metallothionein 1H
NDRG1 N-myc downstream regulated 1
PERP PERP, TP53 apoptosis effector
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
POSTN periostin, osteoblast specific factor
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1
RAE1 ribonucleic acid export 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SULF1 sulfatase 1
TRAPPC3 trafficking protein particle complex 3
VNN1 vanin 1