BRD-K36740062_GSK-1070916_A549_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K36740062_GSK-1070916_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLU clusterin
CXADR coxsackie virus and adenovirus receptor
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDB2 damage-specific DNA binding protein 2, 48kDa
EGFR epidermal growth factor receptor
EHD3 EH-domain containing 3
EIF5A eukaryotic translation initiation factor 5A
FAM134B family with sequence similarity 134, member B
FDXR ferredoxin reductase
GADD45A growth arrest and DNA-damage-inducible, alpha
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
LXN latexin
METTL7A methyltransferase like 7A
MME membrane metallo-endopeptidase
RPS27L ribosomal protein S27-like
SESN1 sestrin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNIP1 TNFAIP3 interacting protein 1
TP53I3 tumor protein p53 inducible protein 3
TRIM22 tripartite motif containing 22
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
COL6A2 collagen, type VI, alpha 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HOPX HOP homeobox
LYN LYN proto-oncogene, Src family tyrosine kinase
MEIS1 Meis homeobox 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
TPM4 tropomyosin 4