BRD-K36737713_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K36737713_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CACYBP calcyclin binding protein
CD200 CD200 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CGRRF1 cell growth regulator with ring finger domain 1
CSRP1 cysteine and glycine-rich protein 1
CTSL cathepsin L
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
GCLM glutamate-cysteine ligase, modifier subunit
H2BFS H2B histone family, member S (pseudogene)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MRPL18 mitochondrial ribosomal protein L18
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NAMPT nicotinamide phosphoribosyltransferase
PIR pirin (iron-binding nuclear protein)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
S100A8 S100 calcium binding protein A8
SCG5 secretogranin V
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
SRGN serglycin
TMEM176B transmembrane protein 176B
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
VCAM1 vascular cell adhesion molecule 1
ZNF410 zinc finger protein 410

decreased expression

Symbol Name
CAV2 caveolin 2
CTGF connective tissue growth factor
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GNAS GNAS complex locus
IFITM3 interferon induced transmembrane protein 3
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
OPHN1 oligophrenin 1
PEG10 paternally expressed 10
PLK1 polo-like kinase 1
RIN2 Ras and Rab interactor 2
SEPT9 septin 9
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3