BRD-K36363294_I-BET151_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K36363294_I-BET151_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTB actin, beta
ANXA3 annexin A3
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CCDC92 coiled-coil domain containing 92
CELF2 CUGBP, Elav-like family member 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENO1 enolase 1, (alpha)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
FAM65B family with sequence similarity 65, member B
FOLR1 folate receptor 1 (adult)
GCA grancalcin, EF-hand calcium binding protein
GRN granulin
GSTM3 glutathione S-transferase mu 3 (brain)
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HPRT1 hypoxanthine phosphoribosyltransferase 1
IGKC immunoglobulin kappa constant
MAMLD1 mastermind-like domain containing 1
MXRA7 matrix-remodelling associated 7
MYO6 myosin VI
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OXA1L oxidase (cytochrome c) assembly 1-like
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLS3 plastin 3
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
RGS2 regulator of G-protein signaling 2
RRAGD Ras-related GTP binding D
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCG2 secretogranin II
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein
VDAC1 voltage-dependent anion channel 1
ZIC1 Zic family member 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACTG2 actin, gamma 2, smooth muscle, enteric
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANPEP alanyl (membrane) aminopeptidase
C1S complement component 1, s subcomponent
C3 complement component 3
CA12 carbonic anhydrase XII
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL20 chemokine (C-C motif) ligand 20
COL6A3 collagen, type VI, alpha 3
CSTA cystatin A (stefin A)
CTSB cathepsin B
DES desmin
EMP2 epithelial membrane protein 2
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPX3 glutathione peroxidase 3
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
KRT15 keratin 15, type I
LCN2 lipocalin 2
LPAR6 lysophosphatidic acid receptor 6
LYZ lysozyme
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3
MGLL monoglyceride lipase
MMP9 matrix metallopeptidase 9
MSMB microseminoprotein, beta-
MUC4 mucin 4, cell surface associated
MYH11 myosin, heavy chain 11, smooth muscle
PDGFC platelet derived growth factor C
PFDN4 prefoldin subunit 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLN phospholamban
PTGES prostaglandin E synthase
RAB25 RAB25, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A4 S100 calcium binding protein A4
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SNAP25 synaptosomal-associated protein, 25kDa
SOD2 superoxide dismutase 2, mitochondrial
TACC2 transforming, acidic coiled-coil containing protein 2
TMEM100 transmembrane protein 100
TMEM176B transmembrane protein 176B
TSPAN1 tetraspanin 1
VAMP8 vesicle-associated membrane protein 8
YME1L1 YME1-like 1 ATPase