BRD-K36363294_I-BET151_HT29_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

151 genes differentially expressed following the BRD-K36363294_I-BET151_HT29_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AAMDC adipogenesis associated, Mth938 domain containing
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
ANXA4 annexin A4
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
BEX1 brain expressed, X-linked 1
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BTBD3 BTB (POZ) domain containing 3
BZW2 basic leucine zipper and W2 domains 2
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCDC92 coiled-coil domain containing 92
CCNG2 cyclin G2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLCN3 chloride channel, voltage-sensitive 3
COL13A1 collagen, type XIII, alpha 1
COL21A1 collagen, type XXI, alpha 1
CPNE3 copine III
CTSA cathepsin A
DDAH2 dimethylarginine dimethylaminohydrolase 2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEFB1 defensin, beta 1
DUSP10 dual specificity phosphatase 10
DUSP6 dual specificity phosphatase 6
DYNLRB1 dynein, light chain, roadblock-type 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM134A family with sequence similarity 134, member A
FAM50A family with sequence similarity 50, member A
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
GSN gelsolin
GSTM3 glutathione S-transferase mu 3 (brain)
GSTT1 glutathione S-transferase theta 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BK histone cluster 1, H2bk
HIST1H3H histone cluster 1, H3h
HSPA1A heat shock 70kDa protein 1A
IER5 immediate early response 5
IL6ST interleukin 6 signal transducer
JAG1 jagged 1
KDM5D lysine (K)-specific demethylase 5D
KIAA1033 KIAA1033
KIF2C kinesin family member 2C
KLF4 Kruppel-like factor 4 (gut)
LAGE3 L antigen family, member 3
LCN2 lipocalin 2
LGALS1 lectin, galactoside-binding, soluble, 1
LGMN legumain
NBPF10 neuroblastoma breakpoint family, member 10
NDRG1 N-myc downstream regulated 1
NEU1 sialidase 1 (lysosomal sialidase)
NOTCH2NL notch 2 N-terminal like
NPC2 Niemann-Pick disease, type C2
NPIPB3 nuclear pore complex interacting protein family, member B3
OXA1L oxidase (cytochrome c) assembly 1-like
PALLD palladin, cytoskeletal associated protein
PDZK1IP1 PDZK1 interacting protein 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNMA1 paraneoplastic Ma antigen 1
PPAP2B phosphatidic acid phosphatase type 2B
PRAME preferentially expressed antigen in melanoma
PTCH1 patched 1
RAB31 RAB31, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
RRAGC Ras-related GTP binding C
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAND1 SCAN domain containing 1
SOSTDC1 sclerostin domain containing 1
SQSTM1 sequestosome 1
SST somatostatin
STXBP1 syntaxin binding protein 1
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP2 TIMP metallopeptidase inhibitor 2
TKTL1 transketolase-like 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM2 transmembrane protein 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRA2A transformer 2 alpha homolog (Drosophila)
TUBA1A tubulin, alpha 1a
UBE2A ubiquitin-conjugating enzyme E2A

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
AREG amphiregulin
ATF5 activating transcription factor 5
AUTS2 autism susceptibility candidate 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCAT1 branched chain amino-acid transaminase 1, cytosolic
CALB1 calbindin 1, 28kDa
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC86 coiled-coil domain containing 86
CCNA2 cyclin A2
CEMIP cell migration inducing protein, hyaluronan binding
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
COL10A1 collagen, type X, alpha 1
COL15A1 collagen, type XV, alpha 1
COL6A2 collagen, type VI, alpha 2
CRYZ crystallin, zeta (quinone reductase)
CXCL12 chemokine (C-X-C motif) ligand 12
DAZAP1 DAZ associated protein 1
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF5A eukaryotic translation initiation factor 5A
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGFBP1 fibroblast growth factor binding protein 1
FOSL1 FOS-like antigen 1
FSCN1 fascin actin-bundling protein 1
FXYD5 FXYD domain containing ion transport regulator 5
GBP2 guanylate binding protein 2, interferon-inducible
IARS isoleucyl-tRNA synthetase
IFRD2 interferon-related developmental regulator 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IPO13 importin 13
IPO5 importin 5
KRT18 keratin 18, type I
LMNB1 lamin B1
LOXL1 lysyl oxidase-like 1
MAL mal, T-cell differentiation protein
MRTO4 mRNA turnover 4 homolog (S. cerevisiae)
MSH6 mutS homolog 6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NLGN4X neuroligin 4, X-linked
NOLC1 nucleolar and coiled-body phosphoprotein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDLIM1 PDZ and LIM domain 1
PEA15 phosphoprotein enriched in astrocytes 15
PIP prolactin-induced protein
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PXMP2 peroxisomal membrane protein 2, 22kDa
PYCR1 pyrroline-5-carboxylate reductase 1
RAD23B RAD23 homolog B (S. cerevisiae)
RAI14 retinoic acid induced 14
RCC1 regulator of chromosome condensation 1
RFC3 replication factor C (activator 1) 3, 38kDa
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SCEL sciellin
SET SET nuclear proto-oncogene
SLC38A1 solute carrier family 38, member 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SRM spermidine synthase
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STS steroid sulfatase (microsomal), isozyme S
THBS2 thrombospondin 2
TMEM109 transmembrane protein 109
TMPO thymopoietin
TRIM14 tripartite motif containing 14
XIST X inactive specific transcript (non-protein coding)
ZNF232 zinc finger protein 232