BRD-K36363294_I-BET151_A549_24_h_0.37_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K36363294_I-BET151_A549_24_h_0.37_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADI1 acireductone dioxygenase 1
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ARG2 arginase 2
CCDC85B coiled-coil domain containing 85B
CXADR coxsackie virus and adenovirus receptor
EYA1 EYA transcriptional coactivator and phosphatase 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
TFRC transferrin receptor

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
AQP3 aquaporin 3 (Gill blood group)
ARL4C ADP-ribosylation factor-like 4C
C5 complement component 5
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CST1 cystatin SN
CXCL14 chemokine (C-X-C motif) ligand 14
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EDN1 endothelin 1
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
GRB14 growth factor receptor-bound protein 14
HMOX1 heme oxygenase 1
IGFBP3 insulin-like growth factor binding protein 3
JADE2 jade family PHD finger 2
LY6E lymphocyte antigen 6 complex, locus E
NMI N-myc (and STAT) interactor
OLFML3 olfactomedin-like 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RBPMS RNA binding protein with multiple splicing
RGS2 regulator of G-protein signaling 2
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SPATS2L spermatogenesis associated, serine-rich 2-like
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNNT1 troponin T type 1 (skeletal, slow)
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VCAN versican