BRD-K36363294_I-BET151_A375_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-K36363294_I-BET151_A375_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP13 A kinase (PRKA) anchor protein 13
ALDOA aldolase A, fructose-bisphosphate
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCDC85B coiled-coil domain containing 85B
CD24 CD24 molecule
CKM creatine kinase, muscle
CORO1C coronin, actin binding protein, 1C
CSRP2 cysteine and glycine-rich protein 2
DPYSL2 dihydropyrimidinase-like 2
EFNB2 ephrin-B2
EGR2 early growth response 2
ENO1 enolase 1, (alpha)
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPX2 glutathione peroxidase 2
GSTM3 glutathione S-transferase mu 3 (brain)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT13 keratin 13, type I
KRT19 keratin 19, type I
LAGE3 L antigen family, member 3
LCN2 lipocalin 2
MEF2C myocyte enhancer factor 2C
MMP7 matrix metallopeptidase 7
NEB nebulin
NQO1 NAD(P)H dehydrogenase, quinone 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLN sarcolipin
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPRR3 small proline-rich protein 3
TFF1 trefoil factor 1
TNNC1 troponin C type 1 (slow)
TOB1 transducer of ERBB2, 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
BEX1 brain expressed, X-linked 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C1S complement component 1, s subcomponent
CFB complement factor B
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLEC2B C-type lectin domain family 2, member B
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COLEC12 collectin sub-family member 12
FN1 fibronectin 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GUSBP11 glucuronidase, beta pseudogene 11
IFITM1 interferon induced transmembrane protein 1
IFITM3 interferon induced transmembrane protein 3
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
JADE2 jade family PHD finger 2
LMO3 LIM domain only 3 (rhombotin-like 2)
LTF lactotransferrin
LYPLA1 lysophospholipase I
MAB21L2 mab-21-like 2 (C. elegans)
MAPT microtubule-associated protein tau
MT1E metallothionein 1E
MT1F metallothionein 1F
NNMT nicotinamide N-methyltransferase
OXA1L oxidase (cytochrome c) assembly 1-like
PNO1 partner of NOB1 homolog (S. cerevisiae)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RGS5 regulator of G-protein signaling 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SORD sorbitol dehydrogenase
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
TIMP3 TIMP metallopeptidase inhibitor 3
TNS3 tensin 3
TSC22D1 TSC22 domain family, member 1
XIST X inactive specific transcript (non-protein coding)