BRD-K35716340_-666_SW620_6.0_h_12.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

81 genes differentially expressed following the BRD-K35716340_-666_SW620_6.0_h_12.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ASUN asunder spermatogenesis regulator
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CCND2 cyclin D2
CD69 CD69 molecule
CREG1 cellular repressor of E1A-stimulated genes 1
CTSS cathepsin S
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DMD dystrophin
EIF1 eukaryotic translation initiation factor 1
GBP1 guanylate binding protein 1, interferon-inducible
HEPH hephaestin
IFI16 interferon, gamma-inducible protein 16
IGFBP5 insulin-like growth factor binding protein 5
ITM2A integral membrane protein 2A
MN1 meningioma (disrupted in balanced translocation) 1
PDE4B phosphodiesterase 4B, cAMP-specific
PFKM phosphofructokinase, muscle
PLAGL1 pleiomorphic adenoma gene-like 1
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PRNP prion protein
PXDN peroxidasin
RAB40B RAB40B, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SERINC5 serine incorporator 5
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SSPN sarcospan
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK26 serine/threonine protein kinase 26
TOP2A topoisomerase (DNA) II alpha 170kDa
TPD52L1 tumor protein D52-like 1
TRIB3 tribbles pseudokinase 3
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
ARFIP2 ADP-ribosylation factor interacting protein 2
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
CDK6 cyclin-dependent kinase 6
CST3 cystatin C
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
CYBA cytochrome b-245, alpha polypeptide
DEFB1 defensin, beta 1
FABP7 fatty acid binding protein 7, brain
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FOXO3 forkhead box O3
GPX3 glutathione peroxidase 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
JADE1 jade family PHD finger 1
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KLK11 kallikrein-related peptidase 11
LPL lipoprotein lipase
MSLN mesothelin
MT1E metallothionein 1E
MYL9 myosin, light chain 9, regulatory
NFIB nuclear factor I/B
PEBP1 phosphatidylethanolamine binding protein 1
PLK1 polo-like kinase 1
PRDX2 peroxiredoxin 2
QDPR quinoid dihydropteridine reductase
RPL27A ribosomal protein L27a
RPL36 ribosomal protein L36
RPL37A ribosomal protein L37a
S100A2 S100 calcium binding protein A2
SCARB2 scavenger receptor class B, member 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SET SET nuclear proto-oncogene
SORD sorbitol dehydrogenase
STXBP2 syntaxin binding protein 2
TUBB2A tubulin, beta 2A class IIa
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
ZBTB16 zinc finger and BTB domain containing 16