BRD-K35638681_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K35638681_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ARFIP2 ADP-ribosylation factor interacting protein 2
CALM3 calmodulin 3 (phosphorylase kinase, delta)
CALR calreticulin
DDIT4 DNA-damage-inducible transcript 4
DHCR24 24-dehydrocholesterol reductase
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IDI1 isopentenyl-diphosphate delta isomerase 1
IER3 immediate early response 3
INSIG1 insulin induced gene 1
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
LDLR low density lipoprotein receptor
LRRC59 leucine rich repeat containing 59
LSR lipolysis stimulated lipoprotein receptor
MANF mesencephalic astrocyte-derived neurotrophic factor
MBNL2 muscleblind-like splicing regulator 2
MSMO1 methylsterol monooxygenase 1
NDRG1 N-myc downstream regulated 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
NUCB2 nucleobindin 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PPIB peptidylprolyl isomerase B (cyclophilin B)
RAB25 RAB25, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SQLE squalene epoxidase
SSR4 signal sequence receptor, delta
XBP1 X-box binding protein 1

decreased expression

Symbol Name
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RGS2 regulator of G-protein signaling 2
RSAD2 radical S-adenosyl methionine domain containing 2
RUNX3 runt-related transcription factor 3