BRD-K35573744_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

94 genes differentially expressed following the BRD-K35573744_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BPHL biphenyl hydrolase-like (serine hydrolase)
CD36 CD36 molecule (thrombospondin receptor)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRDL1 chordin-like 1
CKS2 CDC28 protein kinase regulatory subunit 2
DDIT3 DNA-damage-inducible transcript 3
DUSP5 dual specificity phosphatase 5
G6PD glucose-6-phosphate dehydrogenase
GATA3 GATA binding protein 3
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HBD hemoglobin, delta
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H2BG histone cluster 1, H2bg
HIST1H4C histone cluster 1, H4c
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
JCHAIN joining chain of multimeric IgA and IgM
MCUR1 mitochondrial calcium uniporter regulator 1
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
NES nestin
NQO2 NAD(P)H dehydrogenase, quinone 2
PGD phosphogluconate dehydrogenase
POMZP3 POM121 and ZP3 fusion
SCGB2A2 secretoglobin, family 2A, member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SRPX sushi-repeat containing protein, X-linked
TDP2 tyrosyl-DNA phosphodiesterase 2
TUBB2A tubulin, beta 2A class IIa
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase
WARS tryptophanyl-tRNA synthetase
WDR61 WD repeat domain 61

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALCAM activated leukocyte cell adhesion molecule
ANOS1 anosmin 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BMI1 BMI1 proto-oncogene, polycomb ring finger
BTBD3 BTB (POZ) domain containing 3
CA2 carbonic anhydrase II
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL4 chemokine (C-C motif) ligand 4
CPE carboxypeptidase E
CXCL8 chemokine (C-X-C motif) ligand 8
CYTH1 cytohesin 1
DAPK1 death-associated protein kinase 1
DEFA4 defensin, alpha 4, corticostatin
DHCR24 24-dehydrocholesterol reductase
DUT deoxyuridine triphosphatase
EMP1 epithelial membrane protein 1
FABP7 fatty acid binding protein 7, brain
FAM46A family with sequence similarity 46, member A
GPNMB glycoprotein (transmembrane) nmb
HOXA5 homeobox A5
HOXB2 homeobox B2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IQGAP2 IQ motif containing GTPase activating protein 2
ISG15 ISG15 ubiquitin-like modifier
KLF9 Kruppel-like factor 9
KRT17 keratin 17, type I
LMO2 LIM domain only 2 (rhombotin-like 1)
MT1E metallothionein 1E
MTUS1 microtubule associated tumor suppressor 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ORM1 orosomucoid 1
PLAGL1 pleiomorphic adenoma gene-like 1
PRKCH protein kinase C, eta
PSD3 pleckstrin and Sec7 domain containing 3
RBP1 retinol binding protein 1, cellular
RGS1 regulator of G-protein signaling 1
RHOBTB3 Rho-related BTB domain containing 3
RNASET2 ribonuclease T2
SDC2 syndecan 2
SDC4 syndecan 4
SLPI secretory leukocyte peptidase inhibitor
SOD2 superoxide dismutase 2, mitochondrial
TACSTD2 tumor-associated calcium signal transducer 2
TCF4 transcription factor 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM123 transmembrane protein 123
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNS1 tensin 1
TRIL TLR4 interactor with leucine-rich repeats
TWIST1 twist family bHLH transcription factor 1
ZIC1 Zic family member 1