BRD-K35531059_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

83 genes differentially expressed following the BRD-K35531059_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
APOD apolipoprotein D
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCNG2 cyclin G2
CLU clusterin
CPD carboxypeptidase D
CST3 cystatin C
CTTN cortactin
DEPTOR DEP domain containing MTOR-interacting protein
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EFNA1 ephrin-A1
ELF1 E74-like factor 1 (ets domain transcription factor)
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
EXT1 exostosin glycosyltransferase 1
FAM63A family with sequence similarity 63, member A
FOXO4 forkhead box O4
GAA glucosidase, alpha; acid
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GOLPH3L golgi phosphoprotein 3-like
GPX3 glutathione peroxidase 3
H1F0 H1 histone family, member 0
HBP1 HMG-box transcription factor 1
HES1 hes family bHLH transcription factor 1
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H3H histone cluster 1, H3h
HIST3H2A histone cluster 3, H2a
KDM3A lysine (K)-specific demethylase 3A
KLHDC2 kelch domain containing 2
KLHL24 kelch-like family member 24
MANSC1 MANSC domain containing 1
MBTPS1 membrane-bound transcription factor peptidase, site 1
METTL7A methyltransferase like 7A
OXR1 oxidation resistance 1
PBX1 pre-B-cell leukemia homeobox 1
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP prolactin-induced protein
PLIN2 perilipin 2
PNRC1 proline-rich nuclear receptor coactivator 1
RHOB ras homolog family member B
RNF167 ring finger protein 167
SCGB2A2 secretoglobin, family 2A, member 2
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRPS1 trichorhinophalangeal syndrome I
TXNIP thioredoxin interacting protein
VAV3 vav 3 guanine nucleotide exchange factor
VCAM1 vascular cell adhesion molecule 1
VIM vimentin

decreased expression

Symbol Name
BTG3 BTG family, member 3
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
FPGS folylpolyglutamate synthase
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GPNMB glycoprotein (transmembrane) nmb
HBEGF heparin-binding EGF-like growth factor
KCTD5 potassium channel tetramerization domain containing 5
KLF4 Kruppel-like factor 4 (gut)
LUM lumican
MFAP5 microfibrillar associated protein 5
MSLN mesothelin
MUC4 mucin 4, cell surface associated
MYO1B myosin IB
NOV nephroblastoma overexpressed
NR4A2 nuclear receptor subfamily 4, group A, member 2
ODC1 ornithine decarboxylase 1
PLN phospholamban
PODXL podocalyxin-like
POSTN periostin, osteoblast specific factor
RPP38 ribonuclease P/MRP 38kDa subunit
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SPRR3 small proline-rich protein 3
TLR4 toll-like receptor 4