BRD-K35458079_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

36 genes differentially expressed following the BRD-K35458079_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BMP4 bone morphogenetic protein 4
CAST calpastatin
CHN1 chimerin 1
EPAS1 endothelial PAS domain protein 1
FGFR2 fibroblast growth factor receptor 2
GRB7 growth factor receptor-bound protein 7
HOPX HOP homeobox
LMO3 LIM domain only 3 (rhombotin-like 2)
MCUR1 mitochondrial calcium uniporter regulator 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
S100A8 S100 calcium binding protein A8
SIRPA signal-regulatory protein alpha
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
AGR2 anterior gradient 2
ANXA5 annexin A5
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLIC3 chloride intracellular channel 3
CXCL12 chemokine (C-X-C motif) ligand 12
CYBA cytochrome b-245, alpha polypeptide
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GDF15 growth differentiation factor 15
GREB1 growth regulation by estrogen in breast cancer 1
HSPB8 heat shock 22kDa protein 8
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
OPHN1 oligophrenin 1
RPS11 ribosomal protein S11
SOX9 SRY (sex determining region Y)-box 9
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TSPAN8 tetraspanin 8
ZIC1 Zic family member 1