BRD-K35430135_SR 59230A hydrochloride_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

19 genes differentially expressed following the BRD-K35430135_SR 59230A hydrochloride_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
GADD45B growth arrest and DNA-damage-inducible, beta
HOOK2 hook microtubule-tethering protein 2
IFI16 interferon, gamma-inducible protein 16
MFAP5 microfibrillar associated protein 5
MYO1D myosin ID
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AUTS2 autism susceptibility candidate 2
BAG3 BCL2-associated athanogene 3
BID BH3 interacting domain death agonist
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CBR3 carbonyl reductase 3
COL1A2 collagen, type I, alpha 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
MMP1 matrix metallopeptidase 1
SOX4 SRY (sex determining region Y)-box 4