BRD-K35424586_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

103 genes differentially expressed following the BRD-K35424586_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRE5 adhesion G protein-coupled receptor E5
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ALOX5AP arachidonate 5-lipoxygenase-activating protein
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
C4BPA complement component 4 binding protein, alpha
C9ORF3 chromosome 9 open reading frame 3
CCNA1 cyclin A1
CD93 CD93 molecule
CDC42 cell division cycle 42
CFI complement factor I
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHIC2 cysteine-rich hydrophobic domain 2
CLIC4 chloride intracellular channel 4
CNN3 calponin 3, acidic
CTGF connective tissue growth factor
CTSZ cathepsin Z
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DDAH1 dimethylarginine dimethylaminohydrolase 1
DLC1 DLC1 Rho GTPase activating protein
DUSP10 dual specificity phosphatase 10
FBP1 fructose-1,6-bisphosphatase 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GDF15 growth differentiation factor 15
GSN gelsolin
HBB hemoglobin, beta
HIST1H2AC histone cluster 1, H2ac
IER3 immediate early response 3
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1B interleukin 1, beta
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
ISG15 ISG15 ubiquitin-like modifier
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KRT23 keratin 23, type I
LAPTM5 lysosomal protein transmembrane 5
LGALS1 lectin, galactoside-binding, soluble, 1
LMCD1 LIM and cysteine-rich domains 1
LUM lumican
LXN latexin
MALL mal, T-cell differentiation protein-like
MAP2K6 mitogen-activated protein kinase kinase 6
MCAM melanoma cell adhesion molecule
MMP1 matrix metallopeptidase 1
MMP7 matrix metallopeptidase 7
MTUS1 microtubule associated tumor suppressor 1
MX1 MX dynamin-like GTPase 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFIL3 nuclear factor, interleukin 3 regulated
NNMT nicotinamide N-methyltransferase
OLFM4 olfactomedin 4
PALLD palladin, cytoskeletal associated protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAC8 placenta-specific 8
PLS1 plastin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTX3 pentraxin 3, long
RCAN1 regulator of calcineurin 1
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
RPL38 ribosomal protein L38
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SFN stratifin
SMAD3 SMAD family member 3
SOX10 SRY (sex determining region Y)-box 10
SOX4 SRY (sex determining region Y)-box 4
SRGN serglycin
STC2 stanniocalcin 2
SYT11 synaptotagmin XI
TIAM1 T-cell lymphoma invasion and metastasis 1
TM4SF1 transmembrane 4 L six family member 1
TMEM14A transmembrane protein 14A
TMEM45A transmembrane protein 45A
TPD52L1 tumor protein D52-like 1
TSC22D1 TSC22 domain family, member 1
TSPAN13 tetraspanin 13
VTCN1 V-set domain containing T cell activation inhibitor 1
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
BMP2 bone morphogenetic protein 2
CCND1 cyclin D1
CXCL9 chemokine (C-X-C motif) ligand 9
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DKC1 dyskeratosis congenita 1, dyskerin
FAM57A family with sequence similarity 57, member A
FKBP11 FK506 binding protein 11, 19 kDa
GAL galanin/GMAP prepropeptide
IFRD2 interferon-related developmental regulator 2
NCLN nicalin
SHB Src homology 2 domain containing adaptor protein B
STX4 syntaxin 4
TCF4 transcription factor 4
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast)
UBE2J1 ubiquitin-conjugating enzyme E2, J1
WT1 Wilms tumor 1