BRD-K35004659_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K35004659_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALDOC aldolase C, fructose-bisphosphate
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
DDIT4 DNA-damage-inducible transcript 4
ENO1 enolase 1, (alpha)
GOLGA8A golgin A8 family, member A
HEPH hephaestin
HK2 hexokinase 2
LY75 lymphocyte antigen 75
MT1X metallothionein 1X
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGK1 phosphoglycerate kinase 1
PROM1 prominin 1
QPCT glutaminyl-peptide cyclotransferase
S100P S100 calcium binding protein P
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TXNIP thioredoxin interacting protein
VDAC1 voltage-dependent anion channel 1
VIM vimentin
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
AURKA aurora kinase A
CDC20 cell division cycle 20
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF5 eukaryotic translation initiation factor 5
PLK1 polo-like kinase 1
UBE2C ubiquitin-conjugating enzyme E2C